Research Paper Volume 16, Issue 9 pp 7870—7888

Leptin attenuates the osteogenic induction potential of BMP9 by increasing β-catenin malonylation modification via Sirt5 down-regulation


Figure 1. The effects of ovariectomy on bone formation and Leptin levels in OVX SD rats. (A) Micro-CT scanning results of femurs from the OVX and sham SD rats. (B) Quantitative analysis of bone parameters. Bone mineral density (BMD). (CE) ELISA assay results show the levels of Trap, OCN, and Leptin in the serum of OVX and sham rats. (“*” P<0.05, “**” P < 0.01).