Research Paper Volume 16, Issue 9 pp 8019—8030

AURKB promotes colorectal cancer progression by triggering the phosphorylation of histone H3 at serine 10 to activate CCNE1 expression


Figure 4. AURKB regulated CRC progression via CCNE1 in vitro. HCT116 and SW620 cells were divided into three treatment groups, including shNC, shAURKB, and shAURKB + oeCCNE1. (A) Western blot detected the expression of AURKB and CCNE1. (BD) The proliferation (B), colony formation (C), and cell cycle (D) of the treated cells were evaluated. *p < 0.05, **p < 0.01, ***p < 0.001.