Research Paper Volume 16, Issue 9 pp 8019—8030

AURKB promotes colorectal cancer progression by triggering the phosphorylation of histone H3 at serine 10 to activate CCNE1 expression

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Figure 4. AURKB regulated CRC progression via CCNE1 in vitro. HCT116 and SW620 cells were divided into three treatment groups, including shNC, shAURKB, and shAURKB + oeCCNE1. (A) Western blot detected the expression of AURKB and CCNE1. (BD) The proliferation (B), colony formation (C), and cell cycle (D) of the treated cells were evaluated. *p < 0.05, **p < 0.01, ***p < 0.001.