Research Perspective Volume 2, Issue 5 pp 311—314
Quality and quantity control of proteins in senescence
- 1 Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge CB2 0RE, United Kingdom
received: May 5, 2010 ; accepted: May 17, 2010 ; published: May 18, 2010 ;https://doi.org/10.18632/aging.100145
How to Cite
Autophagy has been implicated in aging and age-related diseases but its roles in these processes are far from straightforward: the anti-aging effect of autophagy has been shown in lower eukaryotes, and both pro- and anti-tumorigenic effects of autophagy have also been demonstrated. The new link between autophagy and senescence provides an insight into the diversified downstream effects of autophagy in various cellular contexts.