The telomere protein tankyrase 1 regulates DNA damage responses at telomeres

Sandy Chang

¹Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA

Received: October 12, 2010Accepted: October 18, 2010Published: October 20, 2010

https://doi.org/http://dx.doi.org/10.18632/aging.100221

Copyright: © 2010 Chang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

The proliferative potential of eukaryotic cells is critically dependent upon the maintenance of functional telomeres, the protein-DNA complexes that cap the ends of chromosomes. A paper published in this issue of Aging describes that the telomere protein tankyrase 1 regulates DNA damage responses at telomeres.