Meeting Report Volume 5, Issue 1 pp 84—93
The role of inflammation in age-related disease
- 1 Division of Cancer Biology, NCI, NIH, Bethesda, MD 20892, USA
- 2 Buck Institute for Research on Aging, Novato, CA 94945, USA and Lawrence Berkeley National Laboratory, Berkeley, CA 94702 USA
- 3 Office of the Director, NICHD, NIH, Bethesda, MD 20892, USA
- 4 Division of Environmental Health Sciences, University of California, Berkeley, CA 94720, USA
- 5 Division of Neuroscience, NIA, NIH, Bethesda, MD 20892, USA
- 6 Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
- 7 Division of Allergy, Immunology and Transplantation, NIAID, NIH, Bethesda, MD 20892, USA
- 8 Advanced Medical Research Institute of Canada, Sudbury, ON, P3E 5J1, Canada
- 9 Division of Aging Biology, NIA, NIH, Bethesda, MD 20892, USA
Received: January 26, 2012 Accepted: January 29, 2013 Published: January 30, 2013
https://doi.org/10.18632/aging.100531How to Cite
Abstract
The National Institutes of Health (NIH) Geroscience Interest Group (GSIG) sponsored workshop, The Role of Inflammation in Age-Related Disease, was held September 6th-7th, 2012 in Bethesda, MD. It is now recognized that a mild pro-inflammatory state is correlated with the major degenerative diseases of the elderly. The focus of the workshop was to better understand the origins and consequences of this low level chronic inflammation in order to design appropriate interventional studies aimed at improving healthspan. Four sessions explored the intrinsic, environmental exposures and immune pathways by which chronic inflammation are generated, sustained, and lead to age-associated diseases. At the conclusion of the workshop recommendations to accelerate progress toward understanding the mechanistic bases of chronic disease were identified.