COVID-19 Research Paper Volume 12, Issue 12 pp 11238—11244
Prognosis analysis of patients with mental disorders with COVID-19: a single-center retrospective study
- 1 Psychosis Intensive Care Unit, Affiliated Wuhan Mental Health Center, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
- 2 Department of Dermatology, Wuhan First Hospital, Wuhan, Hubei, China
- 3 Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
- 4 Department of Traditional Chinese Medicine, Wuhan First Hospital, Wuhan, Hubei, China
- 5 Department of Gynecologic Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
- 6 Department of Cardiology, Enshi Tujia and Miao Autonomous Prefecture Central Hospital, Enshi, PR China
- 7 Department of Otorhinolaryngology, Wuhan First Hospital, Wuhan, Hubei, China
Received: April 19, 2020 Accepted: May 14, 2020 Published: June 19, 2020https://doi.org/10.18632/aging.103371
How to Cite
Copyright © 2020 Wan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Our study aimed to investigate the factors affecting the prognosis of patients with mental disorders with COVID-19. All patients with mental disorders who were diagnosed with COVID-19 at the intensive care unit of Wuhan Mental Health Center during the period January 3 to March 1, 2020 were selected. The influence of the baseline characteristics, clinical symptoms, laboratory parameters and the types of mental disorders on prognosis were analyzed. According to their final prognosis, the patients were divided into the deceased group (5 patients) and the cured group (25 patients). The mortality rate of patients with dementia was significantly higher than that of patients with other mental disorders (P = 0.001). The levels of certain laboratory parameters in the serum of dementia patients were significantly increased compared with levels in nondementia patients (WBC count: 10.100±6.147 vs. 5.694±3.383, p = 0.029; neutrophil count: 8.504± 5.993 vs. 3.764 ± 2.733, P = 0.008; BUN: 8.300± 4.072 vs. 4.364 ± 1.196, P = 0.001). Our research indicated that the mortality rate of dementia patients with COVID-19 was higher than that of patients with other mental disorders. A focus on the inflammatory response of dementia patients may provide novel ideas for reducing mortality.