Research Paper Volume 1, Issue 12 pp 1008—1016

Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential

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Figure 2. Total cellular mass growth during senescence induction. HT-p21 cells were grown in 60 mm wells and soluble protein and GFP were measured daily. Closed bars: HT-p21 cells were treated with IPTG (+IPTG). Open bars: Untreated HT-p21 cells (-IPTG). In both proliferating (-IPTG) and non-proliferating (+IPTG) conditions, protein per well and GFP per well were increasing. In panel B, protein was measured in duplicate and shown without standard deviations, therefore statistical difference between –IPTG and + IPTG should not be considered. The panel simply illustrates exponential growth in both conditions.