Research Paper Volume 2, Issue 9 pp 597—611

The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging

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Figure 5. Western blot analysis of pool level of ASK1 in the livers of Klotho(-/-) and Klotho overexpressing mice. Western blot analyses of levels of ASK1 in the livers of (A) Klotho(-/-)(129)and WT (129) mice and (B) the EFmKL46 Klotho overexpressing and WT mice. The bar graphs depict the mean +/- SE of samples from WT, Klotho(-/-) and EFmKL 46 Klotho overexpressing mice.