Priority Research Paper Volume 4, Issue 4 pp 256—269

cep-1/p53-dependent dysplastic pathology of the aging C. elegans gonad

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Figure 10. cep-1/p53 transcript abundance decreases with age. Whole genome expression profiling was used to identify genes that were differentially expressed with age (for complete description, see [19], cep-1/p53 is statistically significantly differentially expressed with age relative to young worms (p<0.05, cep-1/p53 is in Cluster 5 [19]). Each data point represents the cep-1/p53 message levels in a single animal, and expression level is represented relative to mRNA from a pool of young N2 animals [19].