Research Paper Volume 5, Issue 3 pp 155—173

Figure 8. Histological and immunohistochemical examinations of brain tissues. (A) The cortex reveals no typical spongiform degeneration. (B) Several multicore plaques are present in the molecular layer of the cerebellum with a focal distribution. No pathology was seen in the pons and medulla. C: PrP immunostaining demonstrates weak staining with a synaptic pattern and occasional loose fine granular aggregates in the cerebral cortex. D: The molecular layer of the cerebellum shows a remarkable combination of strip-like staining (Ins. 1) and multicore plaques (Ins. 2). No immunostaining was seen in the pons and medulla.