Research Paper Volume 5, Issue 8 pp 607—622

Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production

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Figure 2. Lipid peroxidation in cerebral cortex was greater after 56Fe radiation. (A) Immunohistochemical staining (arrow) of cerebral cortex for 4-hydroxy-2-nonenal (4-HNE) two months after radiation. (B) Quantification of 4-HNE staining two months after exposure presented as mean ± SEM. (C) Immunohistochemical staining (arrow) for 4-HNE twelve months after radiation. (D) Quantification of 4-HNE staining twelve months after radiation presented as mean ± SEM.