Research Paper Volume 6, Issue 2 pp 131—139
Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging
Figure 3. Effect of aging on TLR-stimulated production of cytokines by PMN. In unstimulated vs TLR ligand-stimulated cells, the difference in the production of IL-8 in supernatants of PMN from younger (N=36) and older (N=34) adults. IL-8 was detected by ELISA after stimulation as shown. Values indicate the mean ± SEM concentration of IL-8 produced by PMN. Asterisks indicate statistical significance between younger and older cohorts (p < 0.05).