Research Paper Volume 6, Issue 4 pp 320—334

Figure 3. Quantitative proteomics reveals altered expression of protein subunits in the electron transport chain with aging. (A) Heatmap of the protein expression changes from 5 to 12 months and 12 to 24 months in isolated synaptic mitochondria (log₂ (12/5 months) and (24/12 months)). Proteins highlighted in red were verified orthogonally. (B) Immunoblot orthogonal validation of protein expression for selected proteins in (A).