Research Paper Volume 6, Issue 8 pp 645—660

SIN3 is critical for stress resistance and modulates adult lifespan

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Figure 2. Sin3A knockdown (KD) affects locomotor function. Climbing ability of control (-RU486), SIN3 KD or GFP RNAi (+RU486) flies is indicated. The average percentage of flies that crossed the 30 cm mark on a 30 ml graduated cylinder in a 30 second time period, measured on indicated days is plotted. Error bars represent standard error of the mean. A and B. SIN3 KD I, C and D. SIN3 KD II, E and F. GFP RNAi serves as an additional control. p<0.001 for the comparison of control and SIN3 KD for each data set starting at day eight.