Research Paper Volume 6, Issue 8 pp 645—660

SIN3 is critical for stress resistance and modulates adult lifespan

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Figure 3. Enhanced Sin3A knockdown (KD) paraquat sensitivity is partially suppressed by glutathione. Survival of control (-RU486), SIN3 KD or GFP RNAi (+RU486) flies on 5 mM paraquat is indicated. For glutathione treatment, flies were placed on media containing 0.22mM glutathione for seven days prior to paraquat treament. Error bars represent standard error of the mean. A and B. SIN3 KD. C and D. GFP RNAi serves as an additional control. * p<0.01.