Research Paper Volume 6, Issue 10 pp 835—851

PHA-4/FOXA-regulated microRNA feed forward loops during Caenorhabditis elegans dietary restriction

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Figure 6. Genes regulated by PHA-4,transcriptionally as well as post-transcriptionally using miRNA are involved in important biological functions during DR. (A) The 1073 genes are enriched in GO terms pertaining to protein folding, cellular metabolism and response to external stimuli. GO analysis was performed using GORILA software and visualized with REVIGO. (B) KEGG pathway components for signaling, lysosome and ubiquitin-mediated decay are enriched in genes that are regulated by PHA-4-controlled FFLs.