Research Paper Volume 6, Issue 10 pp 856—872

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

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Figure 3. Network of miRNA-mRNA relationships obtained by the combination of target predictions and a penalized regression analysis integrating miRNA and mRNA expression measurements. Only miRNAs were considered whose expression levels were associated with age. The miRNA nodes are colored blue and the identified target genes yellow.