Research Paper Volume 6, Issue 11 pp 921—930

TAp73 promotes anti-senescence-anabolism not proliferation

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Figure 3. Metabolic Analysis of TAp73 KO mouse Cortex and Hippocampus. Nucleotide metabolism in TAp73 knockout (TA73KO) versus wild-type (WT) mouse cerebral cortex (C) and hippocampus (H) (n=8 biological littermate replicates; age 1 day). These are the two areas of the central nervous system that show developmental defects in the knockout mice. (a) adenosine 5′-monophosphate (AMP), (b) guanosine 5′-monophosphate (5′-GMP). Box indicates upper/lower quartile, bars max/min of distribution. * p<0.05.