Research Paper Volume 6, Issue 12 pp 1019—1032

The suppression of ghrelin signaling mitigates age-associated thermogenic impairment

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Figure 2. Plasma concentrations of active ghrelin, des-acylated ghrelin, and obestatin during aging. Active ghrelin (A), des-acyl ghrelin, DAG (B), obestatin (C), and insulin (D) of young, middle-aged and old WT mice under fed or fasting conditions. Young (4-months), middle-aged (10-months) and old (22-months) mice were used. The mice were fasted overnight. N = 10-12. *p<0.05, fed vs. fasting. #p<0.05, ## P<0.001, young vs. middle-aged or old.