Research Paper Volume 7, Issue 4 pp 241—255

Thyroxine modifies the effects of growth hormone in Ames dwarf mice

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Figure 4. (A) Insulin Receptor (IR), (B) Insulin Receptor Substrate‐1 (IRS‐1), (C) Phosphoinositide 3‐Kinase (PI3K), and (D) Akt2 relative gene expression in female Ames dwarf (df/df) mouse skeletal muscle tissue after growth hormone (GH) and thyroxine (T4) treatment. For A‐D, Normal (N) n = 10; df/df n = 10; df/df GH n = 10; and df/df GH + T4 n = 8. Groups that do not share a superscript show differences with statistical significance (p < 0.05).