Research Paper Volume 8, Issue 5 pp 977—985

Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis

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Figure 6. MAP1S-activated autophagy suppresses tissue fibrosis. A diagram showing MAP1S activates autophagy to directly suppress fibrosis by promoting the turnover of fibronectin and indirectly impact fibrosis by suppressing pyroptosis and inflammation.