Research Paper Volume 8, Issue 6 pp 1184—1197

Reduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner

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Figure 2. SOD2 protein level is decreased in primary human HCC tissues. (a) Immunohistochemistry (IHC) staining of SOD2 in HCC tissues and adjacent non-cancerous liver tissues. Shown are representative images of negative, low, moderate and high SOD2 IHC staining. (b) Box plot graph of SOD2 IHC staining scores in HCC and matching NCL tissues. Data statistical analysis were performed by Sample-Paired t-test. (c) Scatter plot shows SOD2 staining level in individual tumors as a ratio of SOD2 staining in HCC tissues versus paired NCL tissues.