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Online ISSN: 1945-4589
Research Paper
|
Volume 8, Issue 8
|
pp. 1593–1606
Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)
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Figure 1
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Figure 1.
Bedaquiline: Structure and Activity
Bedaquiline, also known as TMC207 and R207910, is a first-in-class diaryl-quinoline compound, that mechanistically inhibits the bacterial ATP-synthase.