Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

Jacob J.E. J.E. Koopman; Jeroen Pijpe; Stefan Böhringer; David van van Bodegom; Ulrika K. K. Eriksson; Hernando Sanchez-Faddeev; Juventus B. B. Ziem; Bas Zwaan; P. Eline Eline Slagboom; Peter de de Knijff; Rudi G.J. G.J. Westendorp

doi:doi:10.18632/aging.100986

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Research Paper Volume 8, Issue 7 pp 1364—1374

Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

Figure 2. Manhattan plots assessing the associations of SNPs with survival. (A) Manhattan plot assessing the associations of SNPs with survival between newborns and old individuals aged 60 years or over. (B) Manhattan plot assessing the associations of SNPs with survival between newborns and middle-aged adults of fertile ages from 20 through 44 years. (C) Manhattan plot assessing the associations of SNPs with survival between middle-aged adults of fertile ages from 20 through 44 years and old individuals aged 60 years or over. The analyses were adjusted for sex. The level of significance is 1.23 × 10⁻⁵, indicated by the red lines.