Research Paper Volume 8, Issue 7 pp 1485—1512

Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels

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Figure 3. CAG length and age of HD onset versus epigenetic age acceleration in HD patients. Results for CAG length and for age of onset can be found in the first two rows and the last two rows, respectively. (A-H) CAG length (x-axis) versus epigenetic age acceleration in (A) all non-cerebellar samples, (B) parietal lobe, (C) frontal lobe, (D) occipital lobe, (E) caudate nucleus, (F) cingulate gyrus, (G) motor cortex, (H) sensory cortex. (I-P) Age of HD motoric onset (x-axis) versus epigenetic age acceleration in (I) all non-cerebellar samples, (J) parietal lobe, (K) frontal lobe, (L) occipital lobe, (M) caudate nucleus, (N) cingulate gyrus, (O) motor cortex, (P) sensory cortex.