Research Paper Volume 8, Issue 8 pp 1735—1758

Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span

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Figure 2. Net significant differences in protein masses between RES and AL. (A) Sum of relative mass gains and losses in RES compared to AL. Right: Only the proteins with significant (P<0.05) mass differences Left: All detected proteins. (B) Relative (left) and absolute (right) mass losses of the 40 most depleted proteins in RES compared to AL. (C) Relative (left) and absolute (right) mass gains of the 40 most accumulated proteins in RES compared to AL. Grey, mitochondrial proteins. Red: chaperome proteins. Yellow: ribosomal proteins. White: others.