Research Paper Volume 8, Issue 8 pp 1790—1801
Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age
Figure 2. Association between ApoE isoforms and propensity to be an LLS offspring. Carriers of the ApoE ε3 isoform were used as reference. Analyses were adjusted for age and sex, and corrected for familial relationships using robust standard errors. A total of 300 participants was ApoE ɛ2 carrier, 1369 participants carried ApoE ɛ3/ɛ3, and 499 participants carried ApoE ɛ4. For these analyses, 62 participants carrying the ε2/ε4 isoform were excluded.