Research Paper Volume 8, Issue 12 pp 3223—3240

Identification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assay

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Figure 5. Effect of S. haenkei treatment on ROS production on MEFs and human fibroblasts. ROS generation were measured after 3 hours of incubation in untreated cells and after H2O2 exposure. Treatment with NAC was used as positive control. Data are expressed as mean ± SEM percentage of basal (100%) DCF fluorescence intensity (FI) of three independent experiments. **p<0.05 treated vs untreated. (a) ROS production in unstressed MEFs; (b) ROS production in MEFs after exposure to H2O2; (c) ROS production in unstressed human fibroblasts; (d) ROS production in human fibroblasts after exposure to H2O2.