Expression of Concern
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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 8, Issue 10 pp 2509—2524
MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway
Figure 5. The miR-346 affects cell proliferation and cell cycle. A549 and SPC-A-1 cells were analyzed after transfection. (A-B) CCK8 assays of A549 and SPC-A-1 cells after transfected with NC, miR-346, si-XPC and ASO-346. (C) Shown are representative photomicrographs of colony formation assay after transfected with NC, miR-346, si-XPC and ASO-346 for fourteen days. (D-E) Cell-cycle analysis was performed forty eight hours following the treatment A549 and SPC-A-1 cells with NC, miR-346, si-XPC and ASO-346. The DNA content was quantified by flow cytometric analysis. Assays were performed in triplicate. *P < 0.001, Means ± SEM was shown. Statistical analysis was conducted using student t-test.