Research Paper Volume 8, Issue 12 pp 3552—3567
Sodium fluoride (NaF) induces the splenic apoptosis via endoplasmic reticulum (ER) stress pathway in vivo and in vitro
Figure 10. Effect of NaF and NaF-combined with 200 μmol/L 4-PBA treatment on apoptosis of cultured splenic lymphocytes at 48 h. (a-h) Two-dimension scatter plots depicting distribution of cells positively stained for Annexin V-PE/7-AAD. (a) CG, (b) LG, (c) MG and (d) HG, (e) CG+4-PBA, (f) LG+4-PBA, (g) MG+4-PBA, (h) HG+4-PBA. (i) Quantitative analysis of total apoptotic lymphocytes. Data are presented with the means ± standard deviation, * p < 0.05, ** p < 0.01, compared with the control group. Data were analyzed by the variance (ANOVA) test of the SPSS 19.0 software.