Research Paper Volume 8, Issue 12 pp 3552—3567

Sodium fluoride (NaF) induces the splenic apoptosis via endoplasmic reticulum (ER) stress pathway in vivo and in vitro

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Figure 9. Effect of NaF and NaF-combined with 4-PBA treatment on protein expression levels of Bip, GRP94, cleaved caspase-12, p-JNK and CHOP in cultured splenic lymphocytes at 48 h. (a) The western blot assay. (b-c) Quantitative analysis of protein expression. Data are presented with the means ± standard deviation, * p < 0.05, ** p < 0.01, compared with the control group. Data were analyzed by the variance (ANOVA) test of the SPSS 19.0 software.