Research Paper Volume 8, Issue 12 pp 3535—3551

Gerosuppression by pan-mTOR inhibitors

Figure 7. Effect of TORINs on senescent morphology of SKBR3 cells induced to senesce by treatment with PD0332991. Cells were treated with selected concentrations of TORINs and 10 µM PD0332991 (PD). After 4-day treatment drugs were washed out and cells were incubated in drug free medium for 2 days and stained for SA-beta-gal. Bar – 100 µm.