Melatonin-micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopenic women following a one-year double-blind RCT and on osteoblast-osteoclast co-cultures

Sifat Maria; Mark H. Swanson; Larry T. Enderby; Frank D’Amico; Brianna Enderby; Rebekah M. Samsonraj; Amel Dudakovic; Andre J. van Wijnen; Paula A. Witt-Enderby

doi:doi:10.18632/aging.101158

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Research Paper Volume 9, Issue 1 pp 256—285

Melatonin-micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopenic women following a one-year double-blind RCT and on osteoblast-osteoclast co-cultures

Figure 12. Potential mechanism underlying MSDK effects on bone formation. The diagram illustrates regulatory and biological relationships between the indicated proteins and treatments.