Research Paper Volume 9, Issue 6 pp 1585—1594

CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630

Figure 3. miR-630 is the direct target of circRNA_100269. (A) Fluorescence intensity was significantly reduced in the miR-630 mimics and wild-type dual-luciferase reporter plasmid-transfected group in the two GC cell lines. (B) Fluorescence showed no significant change in the miR-630 mimics and mutant dual-luciferase reporter plasmid-transfected group in the two GC cell lines. Error bars represent mean of three separate determinations ± standard deviation (SD). Asterisk indicates statistically significant changes: * (P < 0.05), ** (P < 0.01).