Research Paper Volume 9, Issue 11 pp 2302—2315

Selenium preserves keratinocyte stemness and delays senescence by maintaining epidermal adhesion

Figure 6. Sodium selenite allows the preservation of keratinocyte adhesion receptors for the basal layer in SEs during aging at day 60. (A) Immunofluorescence staining of α6 integrin in SEs that were treated (+30 nM) or not (control), and the quantification is expressed in pixel intensity (relative unit). (B) Immunofluorescence staining of β1 integrin in SEs that were treated (+30 nM) or not (control), and the quantification is expressed in pixel intensity (relative unit). Results are the mean ± SD of 5 independent fields from 3 independent samples. Representative photographs are shown; scale bar = 50 µm; E: epidermis; D: dermis. *p<0.05; **p<0.01.