Research Paper Volume 9, Issue 12 pp 2471—2479

MicroRNA-939 inhibits cell proliferation via targeting LRSAM1 in Hirschsprung’s disease

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Figure 1. Mir-939 was upregulated in HSCR tissues and cytobiology change after treating cells with its mimics. (A) Mir-939 was significantly overexpressed in HSCR (n=80) tissues compared with control samples (n=80). Human 293T, SK-N-BE(2), SH-SY5Y cell lines were transfected with miR-939 mimics, upregulated mir-939 suppressed cell proliferation indicated by the CCK-8 assay (B) without impact on cell migration (C), cell cycle (D) and cell apoptosis (E). *indicates significant difference compared with control group, P<0.05.