Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression

Rahul Bhome; Rebecca W. Goh; Marc D. Bullock; Nir Pillar; Stephen M. Thirdborough; Massimiliano Mellone; Reza Mirnezami; Dieter Galea; Kirill Veselkov; Quan Gu; Timothy J. Underwood; John N. Primrose; Olivier De Wever; Noam Shomron; A. Emre Sayan; Alex H. Mirnezami

doi:doi:10.18632/aging.101355

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Research Paper Volume 9, Issue 12 pp 2666—2694

Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression

Figure 5. Differential expression of miRNAs in NOF and CAF exosomes. Hierarchical cluster analysis of miRNAs in NOF and CAF exosomes. The top 20 most changing miRNAs are shown. Blue-red color scale corresponds with fold changes between -1.5 and +1.5. NOF Ex, normal fibroblast exosome; CAF Ex, cancer-associated fibroblast exosome.