Figure 5. SR-mitochondria coupling are decreased in aged mice. (A) Representative images of electron microscopy 20.000X from FDB longitudinal slices of mice from the different groups. (B) Analysis of ER- mito contacs in percentage shows a significant decrease of these structures in the older group when compared to the 6-9 months old group. (C) Length of the SR- mito interface is significantly increased in the adult group and significantly decreased in the old group.