Research Paper Volume 10, Issue 1 pp 83—99

Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

Figure 1. Effects of resveratrol on aging-related histological renal injury. Less expansion of the mesangial area (A; periodic acid–Schiff (PAS), original magnification ×400) and significantly less tubulointerstitial fibrosis (B; Masson’s trichrome, original magnification ×200) were found in the RSV group compared to that in the control (Cont) group. Quantitative assessment of the areas of extracellular matrix in the glomerulus (C) and tubulointerstitial fibrosis (D) in the control and RSV groups, respectively. (*P<0.001).