Figure 3. Distribution of copy number classes of SPATA31 genes between long-lived individuals (n=258) and controls (n=249). Long-lived individuals were older than 96 years and control individuals between 60-75 years at the time of sampling [28,29]. Copy number variations were determined by digital PCR using primers that amplify all possible SPATA31 copies (left) or only SPATA31A copies (right). The distributions are significantly different (both p<< 0.0001, Wilcoxon rank sum test).