Research Paper Volume 10, Issue 5 pp 1089—1102

Repeated superovulation increases the risk of osteoporosis and cardiovascular diseases by accelerating ovarian aging in mice

Figure 6. Ultrastructural changes of the ovarian granulosa cells in both groups. (A-C) The normal ultrastructure in the ovaries of NC mice. Few lipids were observed in the ovaries, and most mitochondria structures were normal. (D-F) The mitochondria were swollen, exhibited decreased matrix density, and developed flocculent dense bodies in the matrix space in the RS group mice. The number of lipid droplets and swollen Golgi complexes were increased in RS group mice. (O: oocyte; N: nucleus of granulosa cells; M: mitochondrial; L: lipid; G: Golgi complex).