Research Paper Volume 10, Issue 6 pp 1294—1305

MicroRNA-506-3p inhibits osteosarcoma cell proliferation and metastasis by suppressing RAB3D expression

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Figure 3. MiR-506-3p inhibited proliferation of osteosarcoma cells. (A, B) MTT assay showing effect of transfecting miR-506-3p mimic/inhibitor on HOS and MG63 cell proliferation. Data are shown as the mean ± SEM. ** P< 0.05 vs. control. (C-F) Western blot and real-time PCR analyses showing the effect of osteosarcoma cell transfection with miR-506-3p mimic/inhibitor expression of CDK4. Data are shown as mean ± SEM. ** P< 0.05