Research Paper Volume 10, Issue 6 pp 1294—1305

MicroRNA-506-3p inhibits osteosarcoma cell proliferation and metastasis by suppressing RAB3D expression

Figure 5. Effects of miR-506-3p and RAB3D siRNAs on HOS cell proliferation and metastasis. (A) MTT assays showing the effects of miR-506-3p and RAB3D siRNAs on cell proliferation. Data are shown as the mean ± SEM. (B) Transwell assays showing the effects of miR-506-3p and RAB3D siRNAs on cell invasiveness. Cells were counted and results represent the mean ± SD of three experiments. (C, D) Western blot and real-time PCR analyses showing the effects of miR-506-3p and RAB3D siRNAs on RAB3D, CDK4 and MMP2 were detected by. Data are shown as mean ± SEM.