Research Paper Volume 10, Issue 8 pp 2016—2036

Lycopene ameliorates oxidative stress in the aging chicken ovary via activation of Nrf2/HO-1 pathway

Figure 6. Effects of lycopene on the antioxidant capacity, cell proliferation and apoptosis in the ovarian tissues of D280 and D580 hens in vitro. (A) Effect of lycopene on antioxidant capacity in ovarian tissues of D280 and D580 hens in vitro. (B) Effect of lycopene on expression of Nrf2, pNrf2 and HO-1, and the mRNA abundance of Nrf2 and HO-1 in ovarian tissues of D280 and D580 hens in vitro. (C) Effect of lycopene on the mRNA abundance of Nrf2/HO-1 downstream genes in the ovarian tissues of D280 and D580 hens in vitro. (D) Effect of lycopene on the expression of proteins related to cell proliferation and apoptosis in the ovarian tissues of D280 and D580 hens in vitro. Each parameter was determined after 72 h of treatment with lycopene (100 ng/mL). Values are expressed as the means±s.e.. Different lowercase letters indicate significant differences (P < 0.05) for the same age.