Research Paper Volume 10, Issue 8 pp 2122—2135

A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention

Figure 5. Activation of the JAK/STAT signaling pathway by CS exposure. A STAT reporter line (10XSTAT) tht was left untreated (A) or exposed to CS (B). LacZ staining of larvae carrying upd-Gal4, UAS-GFP (C, D), upd2-Gal4, UAS-GFP (E, F) or upd3-Gal4, UAS-GFP (G, H). Displayed are isoltaed trachea from non treated larvae (C, E, G) or those exposed to CS (D, F, H).