Research Paper Volume 10, Issue 9 pp 2459—2479

MiR-665 aggravates heart failure via suppressing CD34-mediated coronary microvessel angiogenesis

Figure 1. MiR-665 is up-regulated in endothelial cells of human heart with heart failure. (A) miR-665 increased a lot in endothelial cells of human heart by RNA fluorescent in situ hybridization (FISH) assay (CD31 is a maker for endothelial cells). (B) Representative immunohistochemical staining of CD31 in human heart (control, n = 2; heart failure [HF], n = 5).