Research Paper Volume 10, Issue 9 pp 2459—2479

MiR-665 aggravates heart failure via suppressing CD34-mediated coronary microvessel angiogenesis

Figure 2. MiR-665 impairs endothelium function in vitro. (A) Migration evaluated by transwell experiment in HUVEC cells. (B) Tube formation determined on Matrigel in HUVEC cells. (C) Apoptosis measured by Annexin V/PI flow cytometric analysis in HUVEC cells. (D) Proliferation detected by EdU incorporation assays in HUVEC cells. Data are representative of four experiments, n=4. Data are expressed as mean ± SEM.