Research Paper Volume 10, Issue 10 pp 2668—2683

High expression of the breast cancer susceptibility gene BRCA1 in long-lived termite kings

Figure 5. Tissue-specific expression of several DNA repair genes in termite workers and reproductives. (A) There were significant differences in RsBRCA1 expression between these tissues (n = 6; P < 0.001). RsBRCA1 expression is higher in testes than in ovaries and the fat body (n = 6; P < 0.05). RsBRCA1 expression is higher in the fat body of PKs than in that of workers and SQs (n = 6; P < 0.05). (B) There were significant differences in RsMCPH1 expression between these tissues (n = 6; P < 0.001). RsMCPH1 expression is higher in ovaries and testes than in the fat body of workers and SQs (n = 6; P < 0.05). (C) There were significant differences in RsMLH1 expression between these tissues (n = 6; P < 0.001). RsMLH1 expression is higher in the ovaries and testes than in the fat body of workers and reproductives (n = 6; P < 0.05). (D) There were significant differences in RsXRCC3 expression between these tissues (n = 6; P < 0.001). RsXRCC3 expression is higher in the ovaries and testes than in the fat body of workers and reproductives (n = 6; P < 0.05). (E) There were significant differences in RsCDK1 expression between these tissues (n = 6; P < 0.001). RsCDK1 expression was higher in the ovaries and testes than in the fat body of workers and reproductives (n = 6; P < 0.05). (F) Although there were significant differences in RsMGMT expression between these tissues (n = 6; P < 0.05), post-hoc tests revealed no significant differences (n = 6). Black and gray bars indicate females and males, respectively. Error bars represent the standard error of the mean. Different letters (a–c) over the bars denote significant differences at P < 0.05. FB, fat body; Ova, ovary; Tes, testis.