Research Paper Volume 10, Issue 10 pp 2755—2771

Pretreatment TACC3 expression in locally advanced rectal cancer decreases the response to neoadjuvant chemoradiotherapy

Figure 1. TACC3 expression in biopsy samples. (A) Expression of TACC3 protein in biopsy tumor tissue and normal tissue from 152 rectal cancer patients before neoadjuvant CRT. The level of TACC3 expression was classified as negative, weak, moderate or strong. (Immunohistochemical staining, 100× and 400×). (B) Expression of TACC3 in normal rectal tissue (Immunohistochemical staining, 100× and 400×). (C) Levels of TACC3 mRNA in rectal cancer tissue and normal tissue from 20 patients. (D) Western blot of biopsy tissue from five rectal cancer patients before neoadjuvant CRT.