Research Paper Volume 10, Issue 10 pp 2832—2854

A multi-tissue full lifespan epigenetic clock for mice

Figure 2. Age acceleration due to diet treatments. Results obtained from ridge regression clock. A meta-analysis p-value for the 3 calorie-restriction (CR) experiments is included. (a) Calorie restriction versus standard diet in the C57BL/J strain. (b) Calorie restriction versus standard chow diet in the B6D2F1 strain. (c) Calorie restriction versus standard diet for the HET3 strain. d) Rapamycin enriched diet versus standard diet for the HET3 strain.